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Article

Prolongation of survival following depletion of CD4+CD25+ regulatory T cells in mice with experimental brain tumors.

Journal of neurosurgery - 1 Sept 2006

El Andaloussi Abdeljabar, Han Yu, Lesniak Maciej S

Abstract excerpt

OBJECT: Regulatory CD4+CD25+ T cells have been shown to play an important role in the regulation of the immune response. Whereas the presence of these cells has been associated with immune suppression, the lack of regulatory T (Treg) cells has been shown to induce autoimmunity. The purpose of this study was to define the role of Treg cells in tumors of the central nervous system (CNS). METHODS: The authors...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16961139
DOI: 10.3171/jns.2006.105.3.430

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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