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Article

Detailed characterization of the mouse glioma 261 tumor model for experimental glioblastoma therapy.

Cancer science - 1 Jun 2006

Szatmári Tünde, Lumniczky Katalin, Désaknai Szilvia, Trajcevski Stéphane, Hídvégi Egon J, Hamada Hirofumi, Sáfrány Géza

Abstract excerpt

Mouse glioma 261 (Gl261) cells are used frequently in experimental glioblastoma therapy; however, no detailed description of the Gl261 tumor model is available. Here we present that Gl261 cells carry point mutations in the K-ras and p53 genes. Basal major histocompatibility complex (MHC)I, but not MHCII, expression was detected in Gl261 cells. The introduction of interferon-gamma-encoding genes increased...

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Identifiers

PMID: 16734735
DOI: 10.1111/j.1349-7006.2006.00208.x
PMCID: PMC11159227

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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