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Article

Large genomic deletions delineate Mycobacterium tuberculosis L4 sublineages in South American countries.

PloS one - 1 Jan 2023

Baena Andres, Cabarcas Felipe, Ocampo Juan C, Barrera Luis F, Alzate Juan F

Abstract excerpt

Mycobacterium tuberculosis (Mtb) is still one of the primary pathogens of humans causing tuberculosis (TB) disease. Mtb embraces nine well-defined phylogenetic lineages with biological and geographical disparities. The lineage L4 is the most globally widespread of all lineages and was introduced to America with European colonization. Taking advantage of many genome projects available in public repositories, we...

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PMID: 37205685
DOI: 10.1371/journal.pone.0285417
PMCID: PMC10198500

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