Mechanisms of human cytomegalovirus persistence and latency

Abstract excerpt

Human cytomegalovirus (HCMV) is a ubiquitous beta-herpesvirus that causes severe disease primarily in immunosuppressed individuals. A major characteristic of HCMV with obvious clinical importance is the ability of the virus to establish lifelong infection within the host following the initial acute infection. One strategy used by HCMV to maintain itself within the host is the establishment of cellular sites of...

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