Article
Discovering disease-genes by topological features in human protein-protein interaction network.
Bioinformatics (Oxford, England) - 15 Nov 2006
Xu Jianzhen, Li Yongjin
Abstract excerpt
MOTIVATION: Mining the hereditary disease-genes from human genome is one of the most important tasks in bioinformatics research. A variety of sequence features and functional similarities between known human hereditary disease-genes and those not known to be involved in disease have been systematically examined and efficient classifiers have been constructed based on the identified common patterns. The...
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