Mutation frequencies at defined single codon sites in vesicular stomatitis virus and poliovirus can be increased only slightly by chemical mutagenesis.

doi:10.1128/JVI.64.8.3960-3962.1990

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Article

Mutation frequencies at defined single codon sites in vesicular stomatitis virus and poliovirus can be increased only slightly by chemical mutagenesis.

Journal of virology - 1 Aug 1990

Holland J J, Domingo E, de la Torre J C, Steinhauer D A

Abstract excerpt

Mutagenesis by a variety of chemical mutagens conferred only 1.1- to 2.8-fold increases in mutation frequencies at defined single base sites in vesicular stomatitis virus and poliovirus.

Topics

Animals
Azacitidine
Cell Line
Codon
Ethyl Methanesulfonate
Fluorouracil
Hydrogen-Ion Concentration
Mutagens
Mutation
Nitrous Acid
Poliovirus
RNA, Messenger
Vesicular stomatitis Indiana virus

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