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Article

Protein kinase A regulates constitutive expression of small heat-shock genes in an Msn2/4p-independent and Hsf1p-dependent manner in Saccharomyces cerevisiae.

Genetics - 1 Mar 2005

Ferguson Scott B, Anderson Erik S, Harshaw Robyn B, Thate Tim, Craig Nancy L, Nelson Hillary C M

Abstract excerpt

Hsf1p, the heat-shock transcription factor from Saccharomyces cerevisiae, has a low level of constitutive transcriptional activity and is kept in this state through negative regulation. In an effort to understand this negative regulation, we developed a novel genetic selection that detects altered expression from the HSP26 promoter. Using this reporter strain, we identified mutations and dosage compensators in...

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Share to Gene Expression Regulation, Fungal

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Source

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Identifiers

PMID: 15545649
DOI: 10.1534/genetics.104.034256
PMCID: PMC1449542

Genes

HSF1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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