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Article

Promoter Hypermethylation Profile of Kidney Cancer with New Proapoptotic p53 Target Genes and Clinical Implications

1 Sept 2006

Abstract excerpt

PURPOSE: Risk stratification of renal cell carcinoma is based on the histopathologic classification. Promoter hypermethylation as a mechanism of gene inactivation in renal cell carcinoma has been shown for only a small number of genes. We examined the usefulness of quantitative methylation analysis with a new set of p53 target genes for determining the clinical outcome and aggressiveness of the tumor disease....

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Share to Epigenetics and DNA Methylation
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PMID: 16951219
DOI: 10.1158/1078-0432.ccr-06-0144

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