Use of genotypic selection to detect P53 codon 273 CGT>CTT transversion: application to an occupationally exposed population.

doi:10.1016/j.ijheh.2006.07.001

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Use of genotypic selection to detect P53 codon 273 CGT>CTT transversion: application to an occupationally exposed population.

International journal of hygiene and environmental health - 1 Jan 2007

Carton T, Tan X D, Hartemann P, Joyeux M

Abstract excerpt

CGT>CTT transversion in codon 273 of the P53 tumor-suppressor gene is one of the major mutations detected in human tumors. Within an epidemiological framework, we investigated the use of a genotypic selection method to measure this point mutation. The allele-specific polymerase chain reaction (AS...

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Use of genotypic selection to detect P53 codon 273 CGT>CTT transversion: application to an occupationally exposed population.

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