Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Microarray identifies ADAM family members as key responders to TGF-β1 in alveolar epithelial cells

1 Sept 2006

Abstract excerpt

The molecular mechanisms of Idiopathic Pulmonary Fibrosis (IPF) remain elusive. Transforming Growth Factor beta 1(TGF-beta1) is a key effector cytokine in the development of lung fibrosis. We used microarray and computational biology strategies to identify genes whose expression is significantly altered in alveolar epithelial cells (A549) in response to TGF-beta1, IL-4 and IL-13 and Epstein Barr virus. A549 cells...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
Share to Lung Cancer Treatments and Mutations
Share to Occupational and environmental lung diseases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 16948840
DOI: 10.1186/1465-9921-7-114

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Microarray identifies ADAM family members as key responders to TGF-β1 in alveolar epithelial cellsPMID 16948840Read ↗

Gene expression profiling reveals novel TGFβ targets in adult lung fibroblastsSemantic proximity Read ↗

Gene expression analysis reveals matrilysin as a key regulator of pulmonary fibrosis in mice and humansSemantic proximity Read ↗

A TGFβ-Responsive Gene Signature Is Associated with a Subset of Diffuse Scleroderma with Increased Disease SeveritySemantic proximity Read ↗

High Throughput Determination of TGFβ1/SMAD3 Targets in A549 Lung Epithelial CellsSemantic proximity Read ↗

Global expression profiling of fibroblast responses to transforming growth factor-beta1 reveals the induction of inhibitor of differentiation-1 and provides evidence of smooth muscle cell phenotypic switching.Semantic proximity Read ↗

Adhesion, migration, transcriptional, interferon-inducible, and other signaling molecules newly implicated in cancer susceptibility and resistance of JB6 cells by cDNA microarray analyses.Semantic proximity Read ↗

Regulation of A Disintegrin And Metalloprotease-33 Expression by Transforming Growth Factor-βSemantic proximity Read ↗

Expression and Regulation of a Disintegrin and Metalloproteinase (ADAM) 8 in Experimental AsthmaSemantic proximity Read ↗

Matrix metalloproteinase (MMP)-19-deficient fibroblasts display a profibrotic phenotypeSemantic proximity Read ↗

Modulation of several waves of gene expression during FGF-1 induced epithelial-mesenchymal transition of carcinoma cells.Semantic proximity Read ↗

Methylation-mediated BMPER expression in fibroblast activation in vitro and lung fibrosis in mice in vivoSemantic proximity Read ↗

A-Kinase Anchoring Proteins Diminish TGF-β1/Cigarette Smoke-Induced Epithelial-To-Mesenchymal Transition.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.