Article
Cappuccino mutation in an autoimmune-prone strain of mice suggests a role of platelet function in the progression of immune complex crescentic glomerulonephritis.
Arthritis and rheumatism - 1 Sept 2006
Yoshida Minako, Saiga Kan, Hato Takaaki, Iwaki Shoko, Niiya Toshiyuki, Arita Norimasa, Komori Hiroaki, Tsubaki Takahito, Furukawa Hiroshi, Terada Miho, Maeyama Kazutaka, Nemoto Kyuichi, Nose Masato, Ono Masao
Abstract excerpt
OBJECTIVE: Crescent formation in the renal glomerulus is a typical manifestation of progressive glomerulopathy associated with fatal renal failure; therefore, its prevention is of clinical importance. Little is known about the pathogenic mechanism for crescent formation. This study was undertaken in an attempt to identify the events that are critical for crescent formation in immune complex crescentic...
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