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Article

The role of AtMUS81 in DNA repair and its genetic interaction with the helicase AtRecQ4A.

Nucleic acids research - 1 Jan 2006

Hartung F, Suer S, Bergmann T, Puchta H

Abstract excerpt

The endonuclease MUS81 has been shown in a variety of organisms to be involved in DNA repair in mitotic and meiotic cells. Homologues of the MUS81 gene exist in the genomes of all eukaryotes, pointing to a conserved role of the protein. However, the biological role of MUS81 varies between different eukaryotes. For example, while loss of the gene results in strongly impaired fertility in Saccharomyces cerevisiae...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 16945961
DOI: 10.1093/nar/gkl576
PMCID: PMC1636358

Genes

MUS81

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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The role of AtMUS81 in DNA repair and its genetic interaction with the helicase AtRecQ4A.PMID 16945961Read ↗

Expression and functional analysis of AtMUS81 in Arabidopsis meiosis reveals a role in the second pathway of crossing-over.Semantic proximity Read ↗

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The mismatch repair protein MSH6 regulates somatic recombination in Arabidopsis thalianaSemantic proximity Read ↗

Involvement of mammalian Mus81 in genome integrity and tumor suppression.Semantic proximity Read ↗

Two closely related RecQ helicases have antagonistic roles in homologous recombination and DNA repair in Arabidopsis thaliana.Semantic proximity Read ↗

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The Arabidopsis ROCK-N-ROLLERS gene encodes a homolog of the yeast ATP-dependent DNA helicase MER3 and is required for normal meiotic crossover formation.Semantic proximity Read ↗

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