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Article

Fc gamma R IIIB polymorphisms: their association with clinical manifestations and autoantibodies in SLE patients from western India.

International journal of rheumatic diseases - 1 May 2010

Pradhan Vandana, Deshpande Neha, Nadkarni Anita, Patwardhan Manisha, Surve Prathamesh, Ghosh Kanjaksha

Abstract excerpt

BACKGROUND: Receptors for the Fc fragment of immunoglobulin G (Fc gamma Rs) represent the link between the humoral and cellular immune responses. Polymorphisms of Fc gamma R, mainly IIA, IIB, IIIA, IIIB have been identified as genetic factors influencing susceptibility to disease or disease course of a prototype autoimmune disease like systemic lupus erythematosus (SLE). Fc gamma alleles may be associated with...

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PMID: 20536598
DOI: 10.1111/j.1756-185X.2010.01469.x

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