Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Enhanced Gene Transfer Efficiency in the Murine Striatum and an Orthotopic Glioblastoma Tumor Model, Using AAV-7- and AAV-8-Pseudotyped Vectors

1 Aug 2006

Abstract excerpt

In this study, recombinant AAV vectors pseudotyped with viral capsids derived from AAV serotypes 7 and 8 were evaluated for gene transfer in the murine striatum relative to vectors pseudotyped with AAV serotypes 2, 5, and 6. In comparison with rAAV serotype 2, pseudotyped vectors derived from AAV-7 and AAV-8 have increased transduction efficiency in the murine CNS, with the rank order rAAV-7 > rAAV-8 > rAAV-5 >...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to CRISPR and Genetic Engineering
Share to Herpesvirus Infections and Treatments
Share to Virus-based gene therapy research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 16942441
DOI: 10.1089/hum.2006.17.807

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Enhanced Gene Transfer Efficiency in the Murine Striatum and an Orthotopic Glioblastoma Tumor Model, Using AAV-7- and AAV-8-Pseudotyped VectorsPMID 16942441Read ↗

Comparative Analysis of Adeno-Associated Viral Vector Serotypes 1, 2, 5, 7, And 8 in Mouse BrainSemantic proximity Read ↗

Comparative Transduction Efficiency of AAV Vector Serotypes 1–6 in the Substantia Nigra and Striatum of the Primate BrainSemantic proximity Read ↗

Pseudotyped Lentiviral Vectors for Retrograde Gene Delivery into Target Brain RegionsSemantic proximity Read ↗

Transduction characteristics of adeno-associated virus vectors expressing cap serotypes 7, 8, 9, and Rh10 in the mouse brainSemantic proximity Read ↗

Transduction Patterns of Pseudotyped Lentiviral Vectors in the Nervous SystemSemantic proximity Read ↗

AAV Serotype 8-Mediated Gene Delivery of a Soluble VEGF Receptor to the CNS for the Treatment of GlioblastomaSemantic proximity Read ↗

Transduction of human glial and neuronal tumor cells with different lentivirus vector pseudotypesSemantic proximity Read ↗

Characterisation of axonal retrograde transport of rabies pseudotyped lentiviral vectors for application in gene therapy of motor neuron diseasesSemantic proximity Read ↗

Adeno-Associated Virus Pseudotype 5 Vector Improves Gene Transfer in Arthritic JointsSemantic proximity Read ↗

Repeat Transduction in the Mouse Lung by Using Adeno-Associated Virus Vectors with Different SerotypesSemantic proximity Read ↗

In Vivo Transduction of Cerebellar Purkinje Cells Using Adeno-Associated Virus VectorsSemantic proximity Read ↗

Rabies virus glycoprotein pseudotyping of lentiviral vectors enables retrograde axonal transport and access to the nervous system after peripheral deliverySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.