Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Pseudotyped Lentiviral Vectors for Retrograde Gene Delivery into Target Brain Regions

2 Aug 2017

Abstract excerpt

Gene transfer through retrograde axonal transport of viral vectors offers a substantial advantage for analyzing roles of specific neuronal pathways or cell types forming complex neural networks. This genetic approach may also be useful in gene therapy trials by enabling delivery of transgenes into a target brain region distant from the injection site of the vectors. Pseudotyping of a lentiviral vector based on...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Herpesvirus Infections and Treatments
Share to RNA Interference and Gene Delivery
Share to Virus-based gene therapy research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 28824385
DOI: 10.3389/fnana.2017.00065

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Pseudotyped Lentiviral Vectors for Retrograde Gene Delivery into Target Brain RegionsPMID 28824385Read ↗

Highly Efficient Retrograde Gene Transfer into Motor Neurons by a Lentiviral Vector Pseudotyped with Fusion GlycoproteinSemantic proximity Read ↗

Transduction Patterns of Pseudotyped Lentiviral Vectors in the Nervous SystemSemantic proximity Read ↗

Rabies virus glycoprotein pseudotyping of lentiviral vectors enables retrograde axonal transport and access to the nervous system after peripheral deliverySemantic proximity Read ↗

Characterisation of axonal retrograde transport of rabies pseudotyped lentiviral vectors for application in gene therapy of motor neuron diseasesSemantic proximity Read ↗

Transneuronal Circuit Analysis With Pseudorabies VirusesSemantic proximity Read ↗

Anterograde or Retrograde Transsynaptic Circuit Tracing in Vertebrates with Vesicular Stomatitis Virus VectorsSemantic proximity Read ↗

Third-generation rabies viral vectors allow nontoxic retrograde targeting of projection neurons with greatly increased efficiencySemantic proximity Read ↗

Viral strategies for studying the brain, including a replication‐restricted self‐amplifying delta‐G vesicular stomatis virus that rapidly expresses transgenes in brain and can generate a multicolor golgi‐like expressionSemantic proximity Read ↗

Optimization of the Fluorescent Protein Expression Level Based on Pseudorabies Virus Bartha Strain for Neural Circuit TracingSemantic proximity Read ↗

Comparative Analysis of Adeno-Associated Viral Vector Serotypes 1, 2, 5, 7, And 8 in Mouse BrainSemantic proximity Read ↗

Pseudo-typed Semliki Forest virus delivers EGFP into neuronsSemantic proximity Read ↗

Gene Expression Profiling with Cre-Conditional Pseudorabies Virus Reveals a Subset of Midbrain Neurons That Participate in Reward CircuitrySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.