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Article

Transduction Patterns of Pseudotyped Lentiviral Vectors in the Nervous System

24 Nov 2003

Abstract excerpt

We have developed a non-primate-based lentiviral vector based on the equine infectious anemia virus (EIAV) for efficient gene transfer to the central and peripheral nervous systems. Previously we have demonstrated that pseudotyping lentiviral vectors with the rabies virus glycoprotein confers retrograde axonal transport to these vectors. In the present study we have successfully produced high-titer EIAV vectors...

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PMID: 14741783
DOI: 10.1016/j.ymthe.2003.09.017

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