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Article

A novel member of the immunoglobulin gene superfamily expressed in rat carcinoma cell lines.

1 Jun 1994

Abstract excerpt

Defined by monoclonal antibody E4, the pE4 antigen is a 66,000-Da glycoprotein which is expressed at the cell surface of rat colon and mammary carcinomas, but only in trace amounts in normal adult rat tissues. To determine the structure of this tumor-associated antigen and to identify its functional domains, we have cloned a cDNA coding for this protein. It encodes a 416-amino acid protein with an expected...

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Identifiers

PMID: 8195207
DOI: 10.1016/s0021-9258(17)40723-x

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