Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Familial inclusion body myositis in a mother and son with different ancestral MHC haplotypes.

Neuromuscular disorders : NMD - 1 Nov 2006

Mastaglia Frank, Price Patricia, Walters Susan, Fabian Vicki, Miller James, Zilko Paul

Abstract excerpt

An Ashkenazi Jewish family in which the mother and a son both have inclusion body myositis (IBM) is reported. The condition developed at an earlier age and was more rapidly progressive and less responsive to treatment in the son than in the mother or other IBM patients in our clinic. Genetic analysis showed that the mother carried alleles of the 8.1 MHC ancestral haplotype (AH; HLA-B8, DRB1*0301), which is found...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Disease Progression
Share to Haplotypes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Major Histocompatibility Complex

Share to Muscle, Skeletal

Share to Myositis, Inclusion Body

Share to Pedigree

Share to Western Australia

Source

Identifiers

PMID: 16934978
DOI: 10.1016/j.nmd.2006.06.009

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 10 closest

Familial inclusion body myositis in a mother and son with different ancestral MHC haplotypes.PMID 16934978Read ↗

Sporadic inclusion body myositis in Japanese is associated with the MHC ancestral haplotype 52.1.Semantic proximity Read ↗

The association of sporadic inclusion body myositis and Sjögren's syndrome in carriers of HLA-DR3 and the 8.1 MHC ancestral haplotype.Semantic proximity Read ↗

Sporadic inclusion body myositis: variability in prevalence and phenotype and influence of the MHC.Semantic proximity Read ↗

Sporadic inclusion body myositis: HLA-DRB1 allele interactions influence disease risk and clinical phenotype.Semantic proximity Read ↗

Two major histocompatibility complex haplotypes influence susceptibility to sporadic inclusion body myositis: critical evaluation of an association with HLA-DR3.Semantic proximity Read ↗

Recombination mapping of the susceptibility region for sporadic inclusion body myositis within the major histocompatibility complex.Semantic proximity Read ↗

HLA allele distribution distinguishes sporadic inclusion body myositis from hereditary inclusion body myopathies.Semantic proximity Read ↗

HLA associations with inclusion body myositisSemantic proximity Read ↗

Supratypes and ancestral haplotypes in IDDM: potential importance of central non-HLA MHC genes.Semantic proximity Read ↗

Autoimmune diabetes mellitus, Hodgkin's disease and Graves' ophthalmopathy in a patient with 8.1 ancestral haplotype.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.