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Article

Sporadic inclusion body myositis: HLA-DRB1 allele interactions influence disease risk and clinical phenotype.

Neuromuscular disorders : NMD - 1 Nov 2009

Mastaglia Frank L, Needham Merrilee, Scott Adrian, James Ian, Zilko Paul, Day Timothy, Kiers Lynette, Corbett Alastair, Witt Campbell S, Allcock Richard, Laing Nigel, Garlepp Michael, Christiansen Frank T

Abstract excerpt

Susceptibility to sIBM is strongly associated with the HLA-DRB1*03 allele and the 8.1 MHC ancestral haplotype (HLA-A1, B8, DRB1*03) but little is known about the effects of allelic interactions at the DRB1 locus or disease-modifying effects of HLA alleles. HLA-A, B and DRB1 genotyping was performed in 80 Australian sIBM cases and the frequencies of different alleles and allele combinations were compared with...

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PMID: 19720533
DOI: 10.1016/j.nmd.2009.07.015

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Sporadic inclusion body myositis: HLA-DRB1 allele interactions influence disease risk and clinical phenotype.PMID 19720533Read ↗

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