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Article

E-cadherin gene polymorphism and risk of urothelial cancer.

Cancer letters - 30 May 2003

Tsukino Hiromasa, Kuroda Yoshiki, Nakao Hiroyuki, Imai Hirohisa, Inatomi Hisato, Kohshi Kiyotaka, Osada Yukio, Katoh Takahiko

Abstract excerpt

The E-cadherin is important in cell-cell adhesion and in the development and maintenance of the epithelial phenotype. A -160C-->A polymorphism in the promoter region of E-cadherin has been shown to decrease gene transcription. This allelic variation may be a potential genetic marker that can help identify those individuals at higher risk for invasive/metastatic disease. We studied the effect of E-cadherin gene...

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PMID: 12767511
DOI: 10.1016/s0304-3835(03)00130-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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