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Article

Expression of a truncated tau protein induces oxidative stress in a rodent model of tauopathy

1 Aug 2006

Abstract excerpt

Truncation of tau protein and oxidative stress have been implicated as important pathogenetic events in tauopathies including Alzheimer's disease (AD). We have generated a transgenic rat model that expresses a human truncated tau protein analogous to a variant form derived from sporadic AD. We employed this model to investigate the relationship between tau protein truncation and oxidative stress. We have found...

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Identifiers

PMID: 16930434
DOI: 10.1111/j.1460-9568.2006.04986.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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