Article
The HEM proteins: a novel family of tissue-specific transmembrane proteins expressed from invertebrates through mammals with an essential function in oogenesis.
Journal of molecular biology - 4 Aug 1995
Baumgartner S, Martin D, Chiquet-Ehrismann R, Sutton J, Desai A, Huang I, Kato K, Hromas R
Abstract excerpt
We report the identification of a new family of proteins, termed the HEM family, which show distinct expression patterns in blood cells and the central nervous system. Through the isolation and characterization of the corresponding brain-specific Drosophila (dhem-2) and rat orthologues (Hem-2), a...
Topics
- Adaptor Proteins, Signal Transducing
- Amino Acid Sequence
- Animals
- Caenorhabditis elegans
- Cloning, Molecular
- Conserved Sequence
- DNA Transposable Elements
- Female
- Gene Expression Regulation, Developmental
- Genes, Insect
- Genes, Lethal
- Hematopoietic System
- Humans