Article
Polymorphisms in the glutathione S-transferase M1, T1, and P1 genes and prostate cancer prognosis.
The Prostate - 1 Oct 2006
Agalliu Ilir, Lin Daniel W, Salinas Claudia A, Feng Ziding, Stanford Janet L
Abstract excerpt
BACKGROUND: Polymorphisms in glutathione S-transferase (GST) genes can increase oxidative stress, which may affect cancer prognosis. The aim of this study was to examine associations between GSTM1, T1, or P1 genetic variants and prostate cancer outcomes. METHODS: A population-based cohort of men (n = 752) from King County, Washington, diagnosed with prostate cancer in 1993-1996, and under long-term surveillance...
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