Article
Human glutathione S-transferase A1, T1, M1, and P1 polymorphisms and susceptibility to prostate cancer in the Japanese population.
Journal of cancer research and clinical oncology - 1 Apr 2005
Komiya Yasuhiro, Tsukino Hiromasa, Nakao Hiroyuki, Kuroda Yoshiki, Imai Hirohisa, Katoh Takahiko
Abstract excerpt
PURPOSE: The incidence of prostate cancer is increasing in low-risk populations such as Japanese. One of the causes of this increase is considered to be associated with the Western diet, especially the high intake of red meat and fat. Glutathione S-transferase (GST) A1, T1, M1, and P1 are phase II enzymes that are important for activation and detoxification of chemical carcinogens. METHODS: In this study, 190...
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