Article
Association between glutathione S-transferases M1 and T1 gene polymorphisms and prostate cancer risk: a systematic review and meta-analysis.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Jan 2014
Cai Qiliang, Wang Zhun, Zhang Wei, Guo Xuemei, Shang Zhiqun, Jiang Ning, Tian Jing, Niu Yuanjie
Abstract excerpt
Genetic polymorphisms in glutathione S-transferases M1 (GSTM1) and T1 (GSTT1) genes have been widely reported and considered to have a significant effect on prostate cancer (PCa) risk, but the results are inconsistent. To evaluate the impact of the GSTM1 and GSTT1 polymorphism on PCa risk, we conducted a comprehensive meta-analysis based on 18 eligible studies. A total of 18 studies, including 7,119 subjects for...
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