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Article

Polymorphisms in glutathione S-transferase genes increase risk of prostate cancer biochemical recurrence differentially by ethnicity and disease severity.

Cancer causes & control : CCC - 1 Dec 2009

Nock Nora L, Bock Cathryn, Neslund-Dudas Christine, Beebe-Dimmer Jennifer, Rundle Andrew, Tang Deliang, Jankowski Michelle, Rybicki Benjamin A

Abstract excerpt

OBJECTIVE: Genetic polymorphisms that modify the detoxifying activity of glutathione S-transferases (GSTs) can affect the level of carcinogenic metabolites created by endogenous steroid hormones and exogenous chemical substances. Although the GSTM1 null genotype has been shown to increase prostat...

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Source

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Identifiers

PMID: 19568698
DOI: 10.1007/s10552-009-9385-0
PMCID: PMC2777237

Genes

GSTT1
BCR
GSTM1
GSTP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19568698-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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