Article
Epithelial tumor cells in bone marrow of patients with colorectal cancer: immunocytochemical detection, phenotypic characterization, and prognostic significance.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 1 May 1990
Schlimok G, Funke I, Bock B, Schweiberer B, Witte J, Riethmüller G
Abstract excerpt
A monoclonal antibody (mAb) directed against the cytokeratin (CK) polypeptide no. 18 specifically expressed in cells derived from simple epithelia was used to detect epithelial tumor cells in bone marrow aspirates. Of 156 patients with colorectal carcinoma, 42 presented with cells at the time of...
Topics
- Antibodies, Monoclonal
- Antigens, Surface
- Bone Marrow
- Carcinoma
- Colorectal Neoplasms
- ErbB Receptors
- Histocompatibility Antigens Class I
- Humans
- Immunohistochemistry
- Keratins
- Ki-67 Antigen
- Phenotype
- Prognosis
- Receptors, Transferrin