Article
Immunocytochemical phenotyping of disseminated tumor cells in bone marrow by uPA receptor and CK18: investigation of sensitivity and specificity of an immunogold/alkaline phosphatase double staining protocol.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society - 1 Feb 1997
Allgayer H, Heiss M M, Riesenberg R, Babic R, Jauch K W, Schildberg F W
Abstract excerpt
Phenotyping of cytokeratin (CK)18-positive cells in bone marrow is gaining increasing importance for future prognostic screening of carcinoma patients. Urokinase-type plasminogen activator receptor (uPA-R) is one example of a potential aggressive marker for those cells. However, a valid and relia...
Topics
- Alkaline Phosphatase
- Bone Marrow Neoplasms
- Enzyme Precursors
- Humans
- Keratins
- Phenotype
- Plasminogen Activators
- Receptors, Cell Surface
- Receptors, Urokinase Plasminogen Activator
- Sensitivity and Specificity
- Staining and Labeling
- Stomach Neoplasms