Article
Sequential immunotyping and genotyping of tumor cells in bone marrow of cancer patients: a model study.
Cytometry - 1 Dec 1998
Müller P, Hempel D, Oruzio D, Ehnle S, Kolloch K, Schlimok G
Abstract excerpt
Epithelial cells can be detected in bone marrow or peripheral stem cell preparations of patients with various kinds of cancer and their presence in bone marrow is of prognostic significance. Characterization of these cells has been hampered by their low frequency. Here we present a method that may allow sequential immunophenotyping and genotyping of epithelial cells in bone marrow. To simulate in vivo situations,...
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