Article
Stochastic search gene suggestion: a Bayesian hierarchical model for gene mapping.
Biometrics - 1 Jun 2006
Swartz Michael D, Kimmel Marek, Mueller Peter, Amos Christopher I
Abstract excerpt
Mapping the genes for a complex disease, such as diabetes or rheumatoid arthritis (RA), involves finding multiple genetic loci that may contribute to the onset of the disease. Pairwise testing of the loci leads to the problem of multiple testing. Looking at haplotypes, or linear sets of loci, avoids multiple tests but results in a contingency table with sparse counts, especially when using marker loci with...
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