Article
Exploring data from genetic association studies using Bayesian variable selection and the Dirichlet process: application to searching for gene × gene patterns.
Genetic epidemiology - 1 Sept 2012
Papathomas Michail, Molitor John, Hoggart Clive, Hastie David, Richardson Sylvia
Abstract excerpt
We construct data exploration tools for recognizing important covariate patterns associated with a phenotype, with particular focus on searching for association with gene-gene patterns. To this end, we propose a new variable selection procedure that employs latent selection weights and compare it to an alternative formulation. The selection procedures are implemented in tandem with a Dirichlet process mixture...
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