Article
Polymorphisms in the promoter region of the angiotensinogen gene are associated with liver cirrhosis in patients with chronic hepatitis B.
Journal of gastroenterology and hepatology - 1 Sept 2006
Xiao Fan, Wei Hongshan, Song Shujing, Li Guoli, Song Chuan
Abstract excerpt
BACKGROUND AND AIMS: It is known that the renin-angiotensin system (RAS) regulates fibrosis. Polymorphisms in the genes of the RAS may contribute to the outcome of liver cirrhosis. Angiotensinogen (AGT), mainly produced in the liver, is the substrate of renin. The aim of this study was to determine whether polymorphisms in the promoter region of the AGT gene are associated with liver cirrhosis in patients with...
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