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Article

Anti-ALS activity of alsin, the product of the ALS2 gene, and activity-dependent neurotrophic factor.

Neuro-degenerative diseases - 1 Jan 2005

Matsuoka Masaaki, Nishimoto Ikuo

Abstract excerpt

Amyotrophic lateral sclerosis (ALS) is an incurable degenerative motoneuronal disease. The complete suppression of motoneuronal death is the ultimate goal of ALS therapy. Two new prosurvival pathways have been recently demonstrated to antagonize neurotoxicity by familial ALS-linked mutant Cu/Zn-s...

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Source

Identifiers

PMID: 16909018
DOI: 10.1159/000089618

Genes

ALS2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16909018-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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