Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The critical role of ocular-infiltrating macrophages in the development of choroidal neovascularization

22 May 2003

Abstract excerpt

Choroidal neovascularization (CNV) is directly related to visual loss in some eye diseases, such as age-related macular degeneration. Although several human histological studies have suggested the participation of macrophages in CNV formation, the precise mechanisms are still not fully understood. In this study, we elucidated the role of ocular-infiltrating macrophages in experimental CNV using CCR2 knockout (KO)...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Glaucoma and retinal disorders
Share to Ocular Diseases and Behçet’s Syndrome
Share to Retinal Diseases and Treatments

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 12832439
DOI: 10.1189/jlb.0902436

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The critical role of ocular-infiltrating macrophages in the development of choroidal neovascularizationPMID 12832439Read ↗

Role of macrophage in ocular neovascularizationSemantic proximity Read ↗

VEGF-production by CCR2-dependent macrophages contributes to laser-induced choroidal neovascularization.Semantic proximity Read ↗

CD11c+ macrophages are proangiogenic and necessary for experimental choroidal neovascularizationSemantic proximity Read ↗

Different distributions of M1 and M2 macrophages in a mouse model of laser-induced choroidal neovascularizationSemantic proximity Read ↗

Macrophages Inhibit Neovascularization in a Murine Model of Age-Related Macular DegenerationSemantic proximity Read ↗

MicroRNA-155 Inhibits Polarization of Macrophages to M2-Type and Suppresses Choroidal Neovascularization.Semantic proximity Read ↗

Intravitreal TSG-6 suppresses laser-induced choroidal neovascularization by inhibiting CCR2+ monocyte recruitmentSemantic proximity Read ↗

Infiltrating monocytes augment alternative complement activation and exacerbate inherited retinal degeneration in a mouse modelSemantic proximity Read ↗

Identification of different macrophage subpopulations with distinct activities in a mouse model of oxygen-induced retinopathySemantic proximity Read ↗

The dynamic changes of macrophage morphology in progression of choroidal neovascularization in laser-induced choroidal neovascularization mice modelSemantic proximity Read ↗

PGE2 promotes macrophage recruitment and neovascularization in murine wet-type AMD modelsSemantic proximity Read ↗

CCL2/CCR2 and CX3CL1/CX3CR1 chemokine axes and their possible involvement in age-related macular degeneration.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.