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Article

Genetic moderators of naltrexone's effects on alcohol cue reactivity.

Alcoholism, clinical and experimental research - 1 Aug 2006

McGeary John E, Monti Peter M, Rohsenow Damaris J, Tidey Jennifer, Swift Robert, Miranda Robert

Abstract excerpt

BACKGROUND: Naltrexone (NTX) reduces drinking and craving in alcoholic individuals in treatment and also in heavy drinkers. Polymorphisms in the D4 dopamine receptor (DRD4) gene and mu-opiate receptor gene (OPRM1) may moderate NTX's effects on craving. This study examined these candidate genes as...

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Source

Identifiers

PMID: 16899031
DOI: 10.1111/j.1530-0277.2006.00156.x

Genes

DRD4
OPRM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16899031-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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