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Article

Potentially reduced fusogenicity of syncytin‐2 in New World monkeys

17 Jan 2023

Abstract excerpt

Syncytin-2 is a membrane fusion protein involved in placenta development that is derived from the endogenous retrovirus envelope gene acquired in the common ancestral lineage of New World and Old World monkeys (OWMs). It is known that syncytin-2 is conserved between apes and OWMs, suggesting its functional importance; however, syncytin-2 of common marmosets (Callithrix jacchus) exhibits lower fusogenic activity...

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PMID: 36647789
DOI: 10.1002/2211-5463.13555

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