Article
Genetic association and brain morphology studies and the chromosome 8p22 pericentriolar material 1 (PCM1) gene in susceptibility to schizophrenia.
Archives of general psychiatry - 1 Aug 2006
Gurling Hugh M D, Critchley Hugo, Datta Susmita R, McQuillin Andrew, Blaveri Ekaterina, Thirumalai Srinivasa, Pimm Jonathan, Krasucki Robert, Kalsi Gursharan, Quested Digby, Lawrence Jacob, Bass Nicholas, Choudhury Khalid, Puri Vinay, O'Daly Owen, Curtis David, Blackwood Douglas, Muir Walter, Malhotra Anil K, Buchanan Robert W, Good Catriona D, Frackowiak Richard S J, Dolan Raymond J
Abstract excerpt
CONTEXT: There is evidence of linkage to a schizophrenia susceptibility locus on chromosome 8p21-22 found by several family linkage studies. OBJECTIVES: To fine map and identify a susceptibility gene for schizophrenia on chromosome 8p22 and to investigate the effect of this genetic susceptibility on an endophenotype of abnormal brain structure using magnetic resonance imaging. DESIGN: Fine mapping and...
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