Article
Developmental changes in multivariate neuroanatomical patterns that predict risk for psychosis in 22q11.2 deletion syndrome.
Journal of psychiatric research - 1 Mar 2011
Gothelf Doron, Hoeft Fumiko, Ueno Takefumi, Sugiura Lisa, Lee Agatha D, Thompson Paul, Reiss Allan L
Abstract excerpt
The primary objective of the current prospective study was to examine developmental patterns of voxel-by-voxel gray and white matter volumes (GMV, WMV, respectively) that would predict psychosis in adolescents with 22q11.2 deletion syndrome (22q11.2DS), the most common known genetic risk factor for schizophrenia. We performed a longitudinal voxel-based morphometry analysis using structural T1 MRI scans from 19...
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