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Article

High-throughput discovery of rare human nucleotide polymorphisms by Ecotilling.

Nucleic acids research - 7 Aug 2006

Till Bradley J, Zerr Troy, Bowers Elisabeth, Greene Elizabeth A, Comai Luca, Henikoff Steven

Abstract excerpt

Human individuals differ from one another at only approximately 0.1% of nucleotide positions, but these single nucleotide differences account for most heritable phenotypic variation. Large-scale efforts to discover and genotype human variation have been limited to common polymorphisms. However, t...

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PMID: 16893952
DOI: 10.1093/nar/gkl479
PMCID: PMC1540726

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16893952-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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