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Article

The FCGR2A--Arg131 variant is no major mortality factor in the elderly--evidence from a German centenarian study.

International journal of immunogenetics - 1 Aug 2006

Flesch B K, Nikolaus S, El Mokhtari N E, Schreiber S, Nebel A

Abstract excerpt

The functional single nucleotide polymorphism rs1801274 in the FCGR2A gene (His131Arg) influences the efficiency of hIgG2 binding, the main isotype produced in response to encapsulated bacteria like Streptococcus pneumoniae and Haemophilus influenzae. In contrast to the receptor with the His131 a...

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Identifiers

PMID: 16893392
DOI: 10.1111/j.1744-313X.2006.00613.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16893392-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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