Article
Genetic association analysis of LRCH1 as an osteoarthritis susceptibility locus.
Rheumatology (Oxford, England) - 1 Feb 2007
Snelling S, Sinsheimer J S, Carr A, Loughlin J
Abstract excerpt
OBJECTIVE: A genetic association with knee osteoarthritis (OA) of a single nucleotide polymorphism (SNP) in intron 1 of the LRCH1 gene was recently reported in a UK Caucasian case-control sample and confirmed in a Newfoundland Caucasian sample. Our objective was to assess whether the SNP was associated with OA in our large UK Caucasian sample. METHODS: The SNP was genotyped in 1521 cases that had undergone...
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