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Article

Genes for directing vacuolar morphogenesis in Saccharomyces cerevisiae. I. Isolation and characterization of two classes of vam mutants.

The Journal of biological chemistry - 15 Sept 1992

Wada Y, Ohsumi Y, Anraku Y

Abstract excerpt

We identified nine VAM genes (for vacuolar morphology) by genetic analyses on mutants with defective vacuolar morphologies and assembly in the yeast Saccharomyces cerevisiae. The nine VAM genes were classified into two classes according to the mutant phenotypes. The class I vam mutants (vam1, vam5, vam8, and vam9) show a few small vesicles that are stained with histochemical markers for the vacuolar compartment....

Topics

Blotting, Western
Calcium
Electrophoresis, Polyacrylamide Gel
Fluorescent Dyes
Fungal Proteins
Genes, Fungal
Isoquinolines
Mutation
Phenotype
Protein Processing, Post-Translational
Saccharomyces cerevisiae

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Temperature

Vacuoles

Source

Identifiers

PMID: 1526998

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1526998-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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