Article
Nucleotide excision repair phenotype of human acute myeloid leukemia cell lines at various stages of differentiation.
Mutation research - 3 Jan 2007
Hsu Pei-hsin, Hanawalt Philip C, Nouspikel Thierry
Abstract excerpt
In previous studies it was shown that nucleotide excision repair (NER) is strongly attenuated at the global genome level in terminally differentiated neuron-like cells. NER was measured in several human acute myeloid leukemia cell lines, before and after differentiation into macrophage-like cells. Repair of cisplatin intrastrand GTG crosslinks in differentiated cells was strongly attenuated. There were also some...
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