Article
Evolution of the HLA-DR1 gene family. Structural and functional analysis of the new allele "DR-BON".
Journal of immunology (Baltimore, Md. : 1950) - 1 Feb 1990
Coppin H L, Avoustin P, Fabron J, Huchenq A, Garnier J M, Thomsen M, De Preval C
Abstract excerpt
The molecules of the MHC are highly polymorphic and involve in Ag presentation; their striking genetic polymorphism allows probable interactions with a large variety of antigenic fragments when these are presented to the TCR. It is therefore of interest to explore the extent of this polymorphism and the mechanisms of its generation. We have studied the class II HLA-DR blank allele DR-BON that has been previously...
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