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Article

Evolution of the HLA-DR1 gene family. Structural and functional analysis of the new allele "DR-BON".

Journal of immunology (Baltimore, Md. : 1950) - 1 Feb 1990

Coppin H L, Avoustin P, Fabron J, Huchenq A, Garnier J M, Thomsen M, De Preval C

Abstract excerpt

The molecules of the MHC are highly polymorphic and involve in Ag presentation; their striking genetic polymorphism allows probable interactions with a large variety of antigenic fragments when these are presented to the TCR. It is therefore of interest to explore the extent of this polymorphism...

Topics

Alleles
Amino Acid Sequence
Base Sequence
Biological Evolution
Cloning, Molecular
Epitopes
Gene Conversion
HLA-DR1 Antigen
Humans
Molecular Sequence Data
Multigene Family
Oligonucleotide Probes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

T-Lymphocytes

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Identifiers

PMID: 1688595

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1688595-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Evolution of the HLA-DR1 gene family. Structural and functional analysis of the new allele "DR-BON".PMID 1688595Read ↗

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