Article
Functional properties of HLA-DR-BON alleles associated with DQw5(w1) and with DQw7(w3): a family study.
Tissue antigens - 1 Aug 1990
Bignon J D, Tkaczuk J, Coppin H, Essaket S, Cesbron A, Cheneau M L, Herfray P, Muller J Y, Huchenq A, Cambon-Thomsen A
Abstract excerpt
Among the DR specificities undefined by serology, DR-BON is peculiar because RFLP cannot distinguish it from the well-defined allele DR1 even if the two specificities are very different functionally. The occurrence of two DR-BON-like alleles in the same family, one associated to the DQw5 split of...
Topics
- Alleles
- Electrophoresis, Gel, Two-Dimensional
- Genomic Library
- HLA-DQ Antigens
- HLA-DR Antigens
- Haplotypes
- Humans
- Lymphocyte Culture Test, Mixed
- Pedigree
- Polymorphism, Restriction Fragment Length