Article
HIV-1 drug resistance genotype results in patients with plasma samples with HIV-1 RNA levels less than 75 copies/mL.
Journal of acquired immune deficiency syndromes (1999) - 1 Sept 2006
Mitsuya Yumi, Winters Mark A, Fessel W Jeffrey, Rhee Soo-Yon, Slome Sally, Flamm Jason, Horberg Michael, Hurley Leo, Klein Daniel, Shafer Robert W
Abstract excerpt
HIV-1 genotypic resistance test results were obtained on clinical samples from 116 patients with plasma HIV-1 RNA levels of less than 75 copies/mL. Genotype validity was confirmed in 49 of 50 patients with a previous or follow-up genotype. The belief that genotypic resistance testing is unreliable in samples with low-level viremia should be reassessed.
Topics
- Anti-HIV Agents
- Drug Resistance, Viral
- Genotype
- HIV Infections
- HIV-1
- Humans
- Phylogeny
- RNA, Viral
- Viral Load