Article
Drug-resistance genotyping in HIV-1 therapy: the VIRADAPT randomised controlled trial.
Lancet (London, England) - 26 Jun 1999
Durant J, Clevenbergh P, Halfon P, Delgiudice P, Porsin S, Simonet P, Montagne N, Boucher C A, Schapiro J M, Dellamonica P
Abstract excerpt
BACKGROUND: Growing evidence has linked HIV-1 resistance mutations and drug failure. The use of genotypic-resistance analysis to assist therapeutic decision-making in patients failing therapy has not been investigated. We assessed the virological and immunological impact of genotypic-resistance testing. METHODS: We did a prospective, open, randomised, controlled study of HIV-1-infected patients in whom...
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