Article
Improved viral suppression after treatment optimization in HIV-infected patients with persistent low-level viremia.
Journal of acquired immune deficiency syndromes (1999) - 15 Dec 2011
McConnell Michael J, Mier-Mota Julian, Flor-Parra Fernando, Martinez-Fernandez Francisco J, Lopez-Cortes Luis F, Viciana Pompeyo, Fernandez-Cuenca Felipe, Perez-Romero Pilar
Abstract excerpt
Optimizing treatment for patients with persistent low-level viremia is complicated because most genotyping tests are validated for viral loads >1000 copies per milliliter. In this study, genotypes of 92 treatment-experienced patients with persistent low-level viremia were determined using an in-house assay. Based on the resistance profiles obtained from genotyping and patient pharmacologic history, patients were...
Topics
- Adult
- Anti-HIV Agents
- Drug Resistance, Viral
- Female
- Gene Expression Regulation, Viral
- Genotype
- HIV Infections
- HIV Protease
- HIV Reverse Transcriptase
- HIV-1
- Humans
- Male
- Middle Aged