Article
Somatic cell nuclear transfer alters peri-implantation trophoblast differentiation in bovine embryos.
Reproduction (Cambridge, England) - 1 Aug 2006
Arnold Daniel R, Bordignon Vilceu, Lefebvre Réjean, Murphy Bruce D, Smith Lawrence C
Abstract excerpt
Abnormal placental development limits success in ruminant pregnancies derived from somatic cell nuclear transfer (SCNT), due to reduction in placentome number and consequently, maternal/fetal exchange. In the primary stages of an epithelial-chorial association, the maternal/fetal interface is characterized by progressive endometrial invasion by specialized trophoblast binucleate/giant cells (TGC). We hypothesized...
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