Article
Nuclear transfer alters placental gene expression and associated histone modifications of the placental-specific imprinted gene pleckstrin homology-like domain, family A, member 2 (PHLDA2) in cattle.
Reproduction, fertility, and development - 1 Mar 2017
Arnold Daniel R, Gaspar Roberta C, da Rocha Carlos V, Sangalli Juliano R, de Bem Tiago H C, Corrêa Carolina A P, Penteado João C T, Meirelles Flavio V, Lopes Flavia L
Abstract excerpt
Abnormal placental development is frequent in nuclear transfer (NT) pregnancies and is likely to be associated with altered epigenetic reprogramming. In the present study, fetal and placental measurements were taken on Day 60 of gestation in cows with pregnancies produced by AI, IVF and NT. Placentas were collected and subjected to histological evaluation, the expression of genes important in trophoblast...
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